Project title:
Detecting elevated left ventricular end diastolic pressure from simultaneously measured femoral pressure waveform and electrocardiogram

--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Grant information:
AHA

--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Relevant publications:
Pahlevan, N.M., Alavi, R., Liu, J., Ramos, M., Hindoyan, A. and Matthews, R.V., 2024. Detecting elevated left ventricular end diastolic pressure from simultaneously measured femoral pressure waveform and electrocardiogram. Physiological Measurement, 45(8), p.085005.

--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Project description:

This dataset is associated with the study titled "Detecting elevated left ventricular end diastolic pressure from simultaneously measured femoral pressure waveform and electrocardiogram." 
The raw data file contains various physiological parameters extracted from rats, including intrinsic frequency features, pressure waveform characteristics, ECG-derived timing intervals, and 
contractility indicators. Each entry in the dataset includes the rat subID and the following parameters:

Parameter                   Description
---------                   -----------
omega1_bpm                 First intrinsic frequency (beats per minute)
omega2_bpm                 Second intrinsic frequency (beats per minute)
phi1                       Initial phase of first intrinsic frequency
phi2                       Initial phase of second intrinsic frequency
RHDN                       Relative height of decoupling at the dicrotic notch
EnvRatio                   Envelope ratio
C_ratio                    Compliance ratio
C_ratio_mod                Modified compliance ratio
omega1_bar                 Normalized omega1 (approach-dependent)
omega2_bar                 Normalized omega2 (approach-dependent)
DicroticNotch              Time location of the dicrotic notch
Duration                   Duration of one cardiac cycle
Pmin                       Minimum pressure value
Pmax                       Maximum pressure value
Diast_max                  Maximum pressure during diastole
Diast_time                 Duration of diastole
p_notch                    Pressure at the dicrotic notch
c                          Model fitting parameter
a1                         Amplitude coefficient of omega1
b1                         Phase shift coefficient of omega1
a2                         Amplitude coefficient of omega2
b2                         Phase shift coefficient of omega2
R1                         Reflection coefficient 1
R2                         Reflection coefficient 2
HR_BPM                     Heart rate (beats per minute), calculated from cycle duration
Site                       Measurement site (e.g., femoral artery)
PDevice                    Pressure measurement device used
name                       Sample or rat identifier
FemP_at_B                  Femoral pressure value at ECG B-point
ECG_Q_to_FemP_B            Time from ECG Q-wave to femoral pressure B-point
ECG_R_to_FemP_B            Time from ECG R-wave to femoral pressure B-point
ECG_Q_to_ECG_S             Time from ECG Q-wave to ECG S-wave
ECG_Q_to_ECG_R             Time from ECG Q-wave to ECG R-wave
FemP_dPdtMax_P             Time of max pressure upstroke (dP/dt max) in femoral waveform
FemP_dPdtMax               Maximum derivative (dP/dt max) of femoral pressure waveform
ECG_PseuR_to_FemP_dpdtMax Time from pseudo-R wave to femoral dP/dt max
CTR (LV-dpdt-Max)          Left ventricular contractility index (maximum dP/dt)

--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Software: 
Matlab, Excel
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------